PW03-032 – Periodic fevers in children

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PW03-032 – Periodic fevers in children

Methods Hospital records and biochemical data were obtained for patients presenting to the paediatric infectious disease clinic with periodic fever syndromes between 2001 and 2011. 68 patients were identified but 30 were excluded as they had a clear focus of infection or no history of recurrent fever on review of the medical records. The clinical diagnosis, patient demographics, aetiology, feve...

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PW03-001 - PFAPA syndrome in Turkish children

Results The median age of onset was 12 months, with a maleto-female ratio of 1,6:1. The length of fever attacks ranged between 2-8 days, and symptom-free intervals between 10-45 days. The most common associated symptoms were pharyngitis (100%), abdominal pain (45,1%), aphthous stomatitis (43,7%), and cervical lymphadenitis (32,4%). During fever flares, the leukocyte count and acute phase reacta...

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PW03-028 – Atypical presentation of CRMO in two children

Introduction Chronic recurrent multifocal osteomyelitis (CRMO) is an autoinflammatory bone disorder that manifests as recurrent flares of inflammatory bone pain, related to one or more foci of nonbacterial osteomyelitis. Patients may present with low grade fever and modest elevation of the erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and white blood cell counts (WBC). We descr...

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OR13-004 – Evidence-based clinical classification criteria for periodic fevers

Methods All FMF, TRAPS, MKD and CAPS patients enrolled in the Eurofever registry until March 2013 were evaluated. For each disease gold standards were considered according to the following criteria: i) clinical validation by centers and disease-principal investigator, ii) confirmative molecular analysis (2 mutations for MEFV with at least one mutation in exon 10, 2 mutations of MVK gene, 1 muta...

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The Prototype of Hereditary Periodic Fevers: Familial Mediterranean Fever

Autoinflammatory disorders are multisystem periodic fever syndromes, and characterized with recurrent unprovoked inflammation of the serosal membranes. Unlike autoimmune disorders, autoinflammatory disorders lack the production of high-titer autoantibodies or antigen-specific T cells. These diseases primarily include hereditary syndromes (Table 1); Familial Mediterrenean fever (FMF), TNF recept...

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ژورنال

عنوان ژورنال: Pediatric Rheumatology

سال: 2013

ISSN: 1546-0096

DOI: 10.1186/1546-0096-11-s1-a258